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Clinical Research Network (CRN)


Clinical Research Network

The Clinical Research Network (CRN), a $1.5 million project, funded by the Foundation for Physical Therapy in 2003 and completed in March 2007.  Headed by Carolee J. Winstein, PT, PhD, FAPTA, and James Gordon, PT, EdD, Department of Biokinesiology and Physical Therapy, University of Southern California, the coordinating center was at the University of Southern California with satellite sites at:  Northwestern Univeristy, Missouri State University, University of California at Los Angeles, Rancho Los Amigos National Rehabilitiation Center, and 23 outpatiend clinics in the greater Los Angeles area.  This multi-site physical therapy clinical research network, also known as PTClinResNet, was establised to assess the effects of strengthening exercises designed to improve muscle performance and movement skill in patients with the following physical disabilities:  adults post-stroke, children with cerebral palsy, adults with chronic spinal cord injury who suffer shoulder pain, and adults whith orthopedic/low back pain.  A common set of valid and reliable outcome measures were used across the projects enabling the investigators to compare the effectiveness of treaments across disabilities and age group.  The preliminary primary outcomes were presented at a session held during APTA's Advocacy Academy in May 2007 in Wasington, DC.

The four research projects were:

PEDALS (Pediatric Endurance Development & Limb Strengthening) evaluated whether a 12 week program of stationary cycling would enhance function in children with cerebral palsy.  The outcomes examined were strength; cardiovascular/respiratory endurance during walking; gross motor performance/perception of change in activities of daily living, sport and play; health-related quality of life; and measures of gait performance.

MUSSEL (Muscle-Specific Strengthening Effectiveness Post Lumbar Microdiscectomy) evaluated the ability of muscle-specific strengthening, after post-lumbar microdiscectomy, to result in improvement in muscle performance, function, quality of life, as well as a reduction in debilitating pain.

STOMPS (Strengthening and Opitmal Movements for Painful Shoulders in Chronic Spinal Cord Injury) evaluated the effectiveness of a combined shoulder exercise and optimization of performance technique program, done by people uisng wheechairs due to chronic spinal cord injury, on pain reduction, increasing performance, as well as improving health-related and overall quality of life.

STEPS (Strengh-Training Effectiveness Post Stroke) evaluated whether functional outcomes, primarily gait speed, were best improved in poststroke patients by: 1) strength training as an adjunct to body weight-supported tradmill training (BWSTT); 2) locomotor-based strength training (BLST) as compared with muscle-specific strength training as an adjunct to BWSTT; and 3) LBST as compared with BWSTT.


CRNews (.pdf)
Gifts to the CRN - Corporate
Gifts to the CRN - Section
History, Projects & Investigators
Web site: PTClinResNet

CRN Update
CRN Update: April 2007 (.pdf)
CRN Update: June 2007 (.pdf)
CRN Update: May 2007 (.pdf)

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